Smart Print Bio Clear Guide: Cytotoxicity and Safety
Check out the technical report on Smart Print Bio Clear Guide resin, attesting to its reduced cytotoxicity and safety for surgical guides.
Check out the technical report on Smart Print Bio Clear Guide resin, attesting to its reduced cytotoxicity and safety for surgical guides.
Cytotoxicity Smart Print Bio Clear Guide (Report)
Safety and biocompatibility are fundamental criteria when choosing materials for dental procedures. This technical article presents the cytotoxicity report of Smart Print Bio Clear Guide, a biocompatible 3D printing resin developed for the fabrication of surgical guides. The study, conducted by the Ecolyzer Moraes laboratory, attests to the material's compliance with rigorous biological safety standards, ensuring peace of mind for dentists and patients.
📊 Quick Technical Summary
The Smart Print Bio Clear Guide is a biocompatible 3D printing resin, whose cytotoxicity report (N.2108146.2021) proves its safety for use in surgical guides, meeting biological safety requirements for contact with oral tissues.
🔬 The Science Behind: Cytotoxicity Report
Biocompatibility is a critical factor for any material that will come into contact with the human body, especially in invasive dental procedures such as implant surgeries. The cytotoxicity test evaluates a material's ability to cause damage to living cells. For the Smart Print Bio Clear Guide, this test was performed following rigorous methodologies to ensure patient safety.
📋 Cytotoxicity Assessment Protocol (Elution Method)
The elution method is widely used to assess the cytotoxicity of materials, simulating the release of substances from the material into the biological environment. Although the provided report does not detail the exact steps of the protocol, it confirms the application of this method for the Smart Print Bio Clear Guide.
General Procedure (Based on Elution Method):
- Step 1: Sample Preparation. The test material (Smart Print Bio Clear Guide) is prepared in a standardized form, usually sterilized, to prevent contamination.
- Step 2: Eluate Extraction. The sample is immersed in a cell culture medium (eluate) for a specific period and temperature (e.g., 24-72 hours at 37°C), allowing any soluble substances to be released.
- Step 3: Cell Culture. Sensitive cell lines (e.g., fibroblasts) are cultured in culture plates until they reach adequate confluence.
- Step 4: Eluate Exposure. The cell culture medium is replaced by the eluate from the test sample. Positive controls (toxic substance) and negative controls (culture medium without eluate) are included for comparison.
- Step 5: Incubation Period. Cells are incubated with the eluate for a determined period (e.g., 24-48 hours) under controlled temperature and CO2 conditions.
- Step 6: Cytotoxicity Assessment. Cell viability and morphology are evaluated by methods such as MTT assay, cell counting, or microscopic observation, comparing the results with controls.
- Step 7: Interpretation of Results. The absence of significant cytotoxic effects indicates that the material is biocompatible and safe for its intended use.
⚠️ Points of Attention:
- Proper sterilization of samples is crucial to avoid false-positive results.
- The choice of cell line and culture medium must be appropriate for the material's application.
- The eluate concentration and exposure time are critical factors influencing the results.
✅ Conclusion and Clinical Application of Smart Print Bio Clear Guide
The cytotoxicity report N.2108146.2021, issued by Ecolyzer Moraes, is a fundamental attestation of the safety of Smart Print Bio Clear Guide. This result assures digital dentistry professionals that the resin can be confidently used in the 3D printing of surgical guides for implants and periodontal surgeries, minimizing biological risks for the patient. SmartDent, as an official distributor, reinforces its commitment to offering solutions that combine technological innovation with maximum safety and biocompatibility.
💡 Invest in Safety and Precision for Your Surgeries
The Smart Print Bio Clear Guide offers the reliability your clinical practice demands. Ensure biocompatible and high-precision surgical guides for your procedures.
Buy Smart Print Bio Clear GuidePerguntas Frequentes
What is the cytotoxicity report for Smart Print Bio Clear Guide?
The cytotoxicity report N.2108146.2021 is a technical document issued by the Ecolyzer Moraes laboratory in DECEMBER/2021. It attests that the Smart Print Bio Clear Guide resin, used for 3D printing of surgical guides, does not show toxic effects on living cells, confirming its biocompatibility and safety for use in dental procedures.
What is the importance of biocompatibility for dental surgical guides?
Biocompatibility is crucial for surgical guides because these devices come into direct contact with soft and hard tissues of the mouth during invasive procedures. A biocompatible material minimizes the risk of adverse reactions, inflammation, cellular toxicity, or rejection, ensuring patient safety and treatment success, especially in implant and periodontal surgeries.
Who conducted the cytotoxicity test for Smart Print Bio Clear Guide?
The cytotoxicity test for Smart Print Bio Clear Guide was performed by the Ecolyzer Moraes testing facility, located at Rua Sebastiano Mazzoni, 263, Vila Moraes, São Paulo/SP, CEP: 04171-000. The study's sponsor was MMTech Projetos Tecnológicos Importação e Exportação LTDA, headquartered in São Carlos/SP.
What method was used to evaluate the resin's cytotoxicity?
The report specifies that the cytotoxicity of Smart Print Bio Clear Guide was evaluated by the Elution Method. This method involves immersing the material in a culture medium to extract soluble substances, which are then tested for their ability to cause damage to living cells in the laboratory.
Is Smart Print Bio Clear Guide safe for use in patients?
Yes, based on Final Report No. N.2108146.2021, Smart Print Bio Clear Guide proved to be non-cytotoxic by the elution method. This means the material is considered safe for contact with biological tissues, making it suitable for manufacturing surgical guides used in dental procedures such as implants and periodontal surgeries.
Where can I purchase Smart Print Bio Clear Guide?
Smart Print Bio Clear Guide can be purchased directly from the SmartDent online store. You can access the product and make a purchase via the link: https://loja.smartdent.com.br/resina-smart-print-clear-guide-. The current price of the resin is R$ 171112.
What are the main applications of Smart Print Bio Clear Guide resin?
Smart Print Bio Clear Guide is a 3D printing resin developed specifically for the fabrication of surgical guides. Its main applications include creating guides for dental implant surgeries and periodontal surgical procedures, where the material's precision and biocompatibility are essential for treatment planning and execution.
How does SmartDent ensure the quality of its products, such as Smart Print Bio Clear Guide?
SmartDent ensures the quality of its products through partnerships with international manufacturers and the performance of rigorous tests, such as the cytotoxicity report for Smart Print Bio Clear Guide. The company positions itself as a reference in digital dentistry, offering solutions that combine technological innovation with maximum safety and compliance with technical and biological standards.
Is there any other biocompatible resin from SmartDent for other applications?
Yes, SmartDent offers a range of biocompatible resins for various applications. For example, the Smart Print Bio Vitality 3D resin (https://loja.smartdent.com.br/resina-smart-print-bio-vitality) is another biocompatible material option available in SmartDent's portfolio, developed to meet other specific clinical needs.
What is the cost of Smart Print Bio Clear Guide?
The cost of Smart Print Bio Clear Guide resin is R$ 171112. This value reflects the quality, proven biocompatibility, and precision that the material offers for the fabrication of surgical guides in clinical and laboratory settings.